Skip to 0 minutes and 13 secondsConsider a patient who has received a course of oral amoxicillin, 500 milligrams 3 times per day for five days. How many defined daily doses has this patient contributed to total antibiotic use in their hospital? So the daily dose is three times 500 milligrams, giving a total of 1.5 grams per day. The DDD for oral amoxicillin is one gram. So each day this patient is receiving 1.5 divided by 1, which is 1.5 defined daily doses. The course is for five days, giving a total for that patient of 7.5 DDD, so this patient has contributed 7.5 defined daily doses to the overall hospital use of antibiotics.

Defined Daily Dose (DDD)

Calculation example

In this video William Malcolm shows you a worked example of a DDD calculation for an individual patient.

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This video is from the free online course:

Antimicrobial Stewardship: Managing Antibiotic Resistance

University of Dundee