Three learners at their computers in an Information Technology room. The tilted down head of a woman in the foreground with two men facing forwards and the back of their and one other computer monitor.
Learners at their computers

End of Week 1

In Week 1’s Steps, we learned about whole genome sequences, and the tools we can use for studying them, such as Artemis, a genome browser.

We learnt about multi-fasta files and how they differ from single fasta sequences. We also learnt about the differences between a finished genome and a draft genome, and the advantages and disadvantages of each. Having a finished genome with its full annotation is very convenient and can be extremely informative. However, all these good features come at a price. Producing finished fully annotated genomes costs more money. Nevertheless, the potentially less reliable draft genomes can be adequate for certain tasks, such as for making comparisons between related genomes. Whether we need access to a finished or draft sequenced genome depends on the analysis that we need to perform.

One of the creators of Artemis, Professor Julian Parkhill, from the Wellcome Sanger Institute, explained why researchers required tools like Artemis. What makes Artemis so unique and why, although it was created in the 2000s, it is still widely used by microbiology researchers.

Later in this course, we will learn more about Artemis, a free genome browser specifically designed for the visualisation of bacterial genomes.

We are looking forward to reading your comments on Week 1.

Tell us and other learners about:

  • your learning experiences and preferences?

  • and which Steps were most interesting to you and why?

  • and where the challenges were for you?

Share your constructive comments in the comments area. Thank- you!

Then next, we look forward to welcoming you to Week 2.

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This article is from the free online course:

Bacterial Genomes: Accessing and Analysing Microbial Genome Data

Wellcome Genome Campus Advanced Courses and Scientific Conferences