End of Week 3

In this Step, we recap on our progress in Week 3 and review our learning.

During Week 3, we compared two genomes, Mycobacterium tuberculosis and Mycobacterium leprae.

Like researchers here at the Wellcome Sanger Institute, you used Artemis, a genome browser, to compare their genetic differences: discovering that the main difference being the greater accumulation of pseudogenes in M. leprae compared to M. tuberculosis. Then we evaluated what this meant for the survival of the species. For M. leprae, we concluded that the accumulation of these pseudogenes - through the accumulation of stop codons in some genes, resulting in the generation of non-functional proteins - could provide an insight into how this bacterium survives in a specific ecological niche.

Well done in completing this Week’s learning: the Peer Review Project!

We know that for some the project combined with peer review was a new way of learning, whilst for others it was a familiar. We hope for all, that this Project Week supported your learning and was enjoyable.

We are interested in learning your views and experiences:

  • what you found most useful

  • what could be improved

  • ask questions about the course - if you have any?

  • add suggestions to help us to refine the course for its next presentation

Please do leave comments in the comments area on your learning experiences during the Peer Review Project Week. Many thanks.

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This article is from the free online course:

Bacterial Genomes: Accessing and Analysing Microbial Genome Data

Wellcome Genome Campus Advanced Courses and Scientific Conferences