Which factor(s) impacts the loading dose ?
Continuing from the previous video, Prof. Brown specifies how a loading dose relates to the volume of distribution (V).
He shows the relationship between elimination and accumulation during a drug infusion, which is important for this lesson.
Can you tell which factor(s) impacts the loading dose for a patient? Is it the volume of distribution (V), clearance (CL), k, or half-life? This concept is explained further in two brain exercises in this video.
What do you think of the relationship between elimination and accumulation during a drug infusion? Please share your thoughts below.
Educator:
Prof. Daniel L. Brown
Clinical Pharmacokinetics: Dosing and Monitoring
Clinical Pharmacokinetics: Dosing and Monitoring
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