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This content is taken from the Taipei Medical University's online course, Clinical Pharmacokinetics: Dosing and Monitoring. Join the course to learn more.

Overview of this week

What can you expect to learn from this week? Professor Daniel Brown is going to explain the topic: What Pharmacists Need to Know about Dosing Aminoglycosides and Vancomycin

Summary of Week 5:

1. The differences between time-dependent and concentration-dependent antibiotic killing.
2. Distinguish between AUC24 and AUIC.
3. Estimate vancomycin CL and identify the target values for vancomycin trough and AUIC.
4. Determine a vancomycin dosing regimen (loading dose, intermittent regimen or continuous infusion) based on CLCr, patient weight and severity of the infection.
5. How extended-interval dosing of aminoglycosides relates to concentration-dependent killing and a post-antibiotic effect.
6. How to use the Hartford nomogram and how to estimate aminoglycoside k and half-life.

We hope you enjoy.

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This article is from the free online course:

Clinical Pharmacokinetics: Dosing and Monitoring

Taipei Medical University