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Monogenic diabetes examples

What is the chance that my children will also have diabetes? Will my grandchildren also be at risk of this type of diabetes?

These are the questions patients often ask, and the answer depends on the origin of the genetic change.

Scenario 1: Autosomal Dominant Inheritance Scenario 2 Scenario 3: Autosomal Recessive Scenario 4: X-linked recessive Scenario 5: Maternally inherited due to mitochondrial DNA (mtDNA) Scenario 6: Parent of origin (Imprinting) Key

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Genomic Medicine: Transforming Patient Care in Diabetes

University of Exeter

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