Skip to 0 minutes and 17 seconds Genomic medicine is transforming the lives of patients with diabetes across the world. Advances in molecular genetics over the last 20 years have led to the discovery of nearly 150 genetic variants that affect our risk of developing type 1 or type 2 diabetes. And mutations in more than 40 genes are now known to cause monogenic diabetes, resulting in improved diagnosis and treatment for many patients. But how does genomics influence patient care? How have these genes been identified? What technology do we use to identify genetic variants? And how can genomic data contribute to precision medicine for patients with diabetes? I’m Maggie Shepherd, and I’m Honorary Clinical Professor of Monogenic Diabetes at the University of Exeter Medical School.
Skip to 1 minute and 6 seconds We’ve gathered together experts from our world leading team of clinicians, scientists, and academics, who, over this four week course, will give you an exciting insight into the impact of genomics and diabetes care. We’ll be exploring genomic medicine through gene discovery and patterns of inheritance through to the latest laboratory techniques and interpretation of genomic data. We’ll be thinking about how to identify patients likely to have a monogenic cause of their diabetes and the effects of receiving a genetic diagnosis on that individual and their family. We’ll also explore the impact of genomics for patients with type 1 and type 2 diabetes, where a combination of multiple genetic effects and environmental factors are involved in disease pathogenesis.
Skip to 1 minute and 54 seconds Through patient stories focusing on their genetic diagnosis, we’ll discover how genomic medicine is transforming lives and improving care. Genetic testing is impacting on healthcare across a range of conditions. And the genomic principles covered in this course can be applied to the thousands of other rare monogenic disorders and also to other complex, multi-factorial diseases. Genetic technologies frequently reach media attention and generate vigorous discussion. There will be lots of opportunity for you to debate the questions raised and to draw your own conclusions. As we enter an age of unprecedented advances in genomic medicine, we’re delighted to be able to share this cutting-edge world class research with you. Join us and find out more.
