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Skip to 0 minutes and 10 seconds The last topic I will talk about today is nutrition and longevity. There are several factors influence the aging process including intrinsic factor and extrinsic factors. What kinds of the factors are intrinsic factors? For example the genetic characteristics so we call centenarians that means the people who are above 100 years old. Why they can live so long compared with other people? because they have more lymphocytes and also have high specific activity of superoxide dismutase. So, that means more lymphocytes and high specific activity of the superoxide dismutase are very important to have a longer lifespan. So what is the superoxide dismutase? It’s a kind of the enzymes and also is the enzyme for Antioxidation.

Skip to 1 minute and 23 seconds So, Antioxidation is very important body defense protected from oxidants’s attack. What is intrinsic factor? That means environmental factors and also nutrient intake. For example, the air pollution the dietry intake and other water pollutions, those are intrinsic factors, which can affect aging process. What is the importance between nutrient intake and aging? Tokyo Metropolitan Institute of Gerontology in 1988 propose the only factors effective in preventing aging are nutrition, exercise, and blood pressure control. I will add one more items as blood sugar control so I think personally nutrition, exercise, blood pressure control as well as blood sugar control are so important for preventing aging process. Franklin said eat to live not live to eat.

Skip to 2 minutes and 49 seconds So you can see eat or the dietary intake is very important for your human lives. And also a Russian physiologist proposed that if you want to live longer, you should have Autointoxication process. What is Autointoxication? That means your body can deal with the toxins produced in large intestine by fecal waste if you don’t excrete those toxin or get rid of these toxins, that means it can be absorbed into your body and to destroy some of your physiological functions. So fecal excretion also very important you have to do every day. And what kind of foods are benefit beneficial for your health? That means can preventing the aging. Some of the fermented products. For example, yogurts and other fermented milk products.

Skip to 4 minutes and 11 seconds Because they contains lactic acid-producing bacilli that can destroy the intestinal microbes responsible for the poisonous waste. So, it’s very important if you have the good bacteria in your large intestine that means you can they can protect your life. If you have the bad bacteria in your large intestine that can destroy and your physiological function and also deposits the poisonous waste in your body. We also see the caloric restriction can prolong your lifespan. Below 50 percents intake of energy takes you into actual calories starvation and death rates increases. So, that means even you want to have caloric restriction but not below 50% of your usual calorie intake.

Skip to 5 minutes and 30 seconds The figure shows the lifespans of the caloric restriction in mice, versus is a non-caloric restriction. So x-axis is the age mice can live. Y -axis is the survival rate in percentage. If you see the cross line and fifty percent survival rate intersect with the x-axis that means the lifespans, average lifespans the mice can live. There are several curves in the figures, green, blue, purple, and red. That’s indicates non-caloric restriction. That means hundred percent of calorie intake. 25 percent of caloric restriction means 75% of calorie intake. 55 percent of caloric restriction that means 45% of the calorie intake and finally 65% of calorie restriction that mean 35% of calorie intake respectfully.

Skip to 6 minutes and 48 seconds So if you see that those four curves which one have the longest lifespan as the red color curve. That means the average lifespan lifespan can be around between 50 and 60 months. But in humans you probably can think about you cannot have too much or overdose caloric restriction so we will suggest that not below 50% calorie restriction in humans.

Eat to live or live to eat?

After we know how long human beings can live, you may wonder why there are so many differences between regions.

In this video, Prof. Chao will explain from the nutrition point of view. You may find that what you eat do matters.

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This video is from the free online course:

Introduction to Nutrition and Food Safety

Taipei Medical University