Clinical Diagnosis of Stages of Chronic Kidney Disease
In this step, Prof. Lee illustrates the different stages of Chronic Kidney Disease based on GFR in mL/min/1.73m2 .
In clinical situation, we will consider Cystatin-C as well.
When estimated GFR > 60 ml/min/1.73 m2 and Cystatin C < 1.0 mg/L, we will consider it as normal kidney function.
When estimated GFR > 60 ml/min/1.73 m2 and Cystatin C > 1.0 mg/L, we will consider it as pre-clinical kidney disease.
When estimated GFR < 60 ml/min/1.73 m2 and Cystatin C > 1.0 mg/L, we will consider it as chronic kidney disease.
Besides, Prof. Lee explains the renal drug excretion and renal drug clearance.
Could you distinguish the difference between the renal clearance of the drug and the metabolite? Please leave your answer below.
Pharmacokinetics: Drug Dosing in Renal Disease
Pharmacokinetics: Drug Dosing in Renal Disease
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