Renal Drug Recovery & Excretion Pathways : Mechanism
In this step, Prof. Lee clarifies Renal Drug Recovery and renal excretion pathways.
To begin with, high urinary recovery (>80%) indicates that the drug is primarily excreted by the kidneys, such as Aminoglycosides and Cephalosporin. Therefore, drugs with high urinary recovery require dosing adjustment in patients in renal failure.
Besides, we can review the three excretion ways again, including filtration, secretion, and reabsorption.
Finally, we can tell the mechanism of renal clearance based on the value of the creatinine clearance.
If you have difficulty on this part, please leave your thoughts below.
Pharmacokinetics: Drug Dosing in Renal Disease
Pharmacokinetics: Drug Dosing in Renal Disease
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