Single and Multiple Intermittent Infusion Equations
Prof. Lee introduces single and multiple intermittent infusion equations in this step. He starts with single intermittent infusion.
To begin with, he illustrates how to calculate the concentration at any time after constant rate IV infusion. Following that, he also demonstrates how to derive the peak concentration after the first infusion, and get the trough concentration after the first dose.
Besides, we can know the concept of steady-state from the diagram in this video.
For multiple intermittent infusion equations, there are five key parameters, including peak concentration at steady-state, trough concentration at steady-state, volume of distribution, dosing interval, and recommended dose.
Therefore, knowing the elimination rate constant, the volume of distribution, the dosing infusion time, and how to perform the intermittent infusion, we will be able to derive the recommend dose.
Ultimately, the infusion rate is equal to the dose divide by cap T, the infusion time.
If you have any questions or thoughts, please share them below.
Pharmacokinetics: Drug Dosing in Renal Disease
Pharmacokinetics: Drug Dosing in Renal Disease
Reach your personal and professional goals
Unlock access to hundreds of expert online courses and degrees from top universities and educators to gain accredited qualifications and professional CV-building certificates.
Join over 18 million learners to launch, switch or build upon your career, all at your own pace, across a wide range of topic areas.
