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Renal Function Tests: GFR, Renal Plasma Flow, and serum maker

Renal Function Tests: GFR, Renal Plasma Flow, and serum maker

In this step, Prof. Lee gives a brief introduction to different kinds of renal function tests, including GFR, renal plasma flow, and serum marker.

There are several methods helping us to determinate GFR, and the one by creatinine clearance is the most common way.

However, there are still two important methods, which are by Tc99m-DTPA clearance and Cr51-EDTA clearance.

Besides, we can use para-amino hippuric acid (PAH) to measure the renal plasma flow, which is an exogenous organic acid filtered and secreted without reabsorption.

Ultimately, we need to know the serum markers, including serum creatinine (Ccr), Blood Urea Nitrogen (BUN), BUN/ Ccr ratio, and Cystatin-C.

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Pharmacokinetics: Drug Dosing in Renal Disease

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