Skip to 0 minutes and 14 secondsProteinuria The same as the previous markers it is an unspecified marker and high proteinuria mat actually from excessive exercise, pregnancy, and also a lots of infectious diseases. Especially for kidney disease, kidney infections or some infective endocarditis and new process diseases are important to contribute to proteinuria and systemic disease the most important one is about diabetes and also some autoimmune diseases and some other and allergic reactions could also that the patient has a science for proteinuria. So using proteinuria to staging or to look at the CKD. We can we also need to consider about if there are other issues other than the patient's decreased renal function. Let's look at the etiology of chronic renal disease. There are two parts.

Skip to 1 minute and 30 secondsWe can actually simply separate into systemic diseases and the disease from renal For systemic diseases, as we mentioned several times diabetes, hypertension are very important etiology. So for all the patient with diabetes and hypertension Carefully following their blood pressure and their glycemic control are very important otherwise that's very easy for the patient to progress to chronic renal disease and those patient with diabetes, we can actually you can use kidney transparent data you will find actually or dialysis data most of patients in that group their original disease is diabetes. And a patient with diabetes and hypertension that will have the increased risk to lead to patient progress to dialysis.

Skip to 2 minutes and 37 secondsSo that's very important to always educate our patient to have a good blood pressure control and a good blood sugar control And also SLE and some important disease such as amyloidosis are also important etiology for systemic disease to chronic renal disease. And those diseases from renal itself including infection. Those infection could actually from glomerulonephritis or interstitial nephritis or some ischemia events that those ischemia renal disease are very important and UTI is important and also those patients with congenital abnormality of kidney that could have very easy to progress to chronic renal disease.

Proteinuria & etiologies of CRF

In this step, Prof. Chen clarifies the proteinuria and etiologies of CRF.

To begin with, proteinuria is an unspecific marker that may indicate some diseases, including infectious, neoplastic, and systemic ones.

Besides, for etiologies of CRF, we need to know the systematic diseases. For instance, for diabetes patients, we should pay attention to their glycemic control.

Therefore, it is very important to educate patients to have a good blood pressure and blood sugar control. Also, SLE and amyloidosis are important etiologies for CRF.

Finally, diseases from renal itself include infection, glomerulonephritis, interstitial nephritis, ischemia renal disease, and UTI.

So we have talked about the etiologies of CRF. In the next step, we will learn Complications of ESRD.

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This video is from the free online course:

Pharmacokinetics: Drug Dosing in Renal Disease

Taipei Medical University