Concentration of IgA in Milk during Lactation
The concentration of IgA in milk increases gradually during lactation. Among them, there is one essential system to help maintain the mammary gland structure.
Professor Nochi will explain further a designed-experiment. In this experiment, thet prepared two groups. One is the normal lactation group, and the other is the forced weaning group. They compare the number of IgA-producing plasma cells in the mammary glands between two groups. The result indicated that the suckling derives signaling from the baby to the mom is essential for the recruitment of IgA-producing plasma cells into the mammary gland. The baby is important, babies stimulate mom to recruit the IgA producing plasma cells in the mammary gland with the mother.
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