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Primary Amenorrhea Due to Anatomical Abnormalities of the Reproductive Tract: Molecular Insight

Primary Amenorrhea Due to Anatomical Abnormalities of the Reproductive Tract: Molecular Insight
Primary Amenorrhea Due to Anatomical Abnormalities of the Reproductive Tract: Molecular Insight

This article explores primary amenorrhoea due to congenital anatomical anomalies of the genital tract, with a particular focus on hypoplasia of the Müllerian duct. Students can discuss the role of genetic anomalies and environmental factors in these problems and give examples of clinical features of patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome. Students can consider how different treatments can improve the quality of life of patients, such as surgical repair of anatomical structures.

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