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Important parameters in the Fish Tank 2: Half-life, Serum Concentration, and AUC

Important parameters in the Fish Tank: Half-life, Serum Concentration, and area under the curve

This video is about the relationship between half-life (t 1/2), serum concentration (C), and Eliminate Rate Constant (k).

After learning how Volume (V) and Clearance (CL) influence k, this time we can learn a new parameter: half-life (t 1/2). Thus we can predict a future concentration by a past concentration, k, and time (t).

Besides, Prof. Brown demonstrates the concept of the area under the curve (AUC) precisely with distinct graphs.

Do you have any question about the parameters so far? Please leave it below.


Prof. Daniel L. Brown

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Clinical Pharmacokinetics: Dosing and Monitoring

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