Important parameters in the Fish Tank 3 : Mean Residence Time and Protein Binding
Prof. Brown illustrates the definition of Mean Residence Time (MRT) in this video. MRT is a measure of drug exposure over time.
He also explains that under some conditions, protein binding will affect clearance (CL), volume of distribution, and pharmacologic effect. We will learn the detail in the next video.
The brain exercise this time is about the relationship between AUC, clearance (CL), and the dose. Do you have any questions? Feel free to leave them below.
Educator:
Prof. Daniel L. Brown
Clinical Pharmacokinetics: Dosing and Monitoring
Clinical Pharmacokinetics: Dosing and Monitoring
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