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How to determine an effective dose : the importance of a loading dose

How to determine an effective dose: the importance of a loading dose

In this video, we start with “How can we determine the safest and most effective dose of the drug for a specific patient?”

Prof. Brown illustrates the outline and the learning goal for this session. He clarifies the 3 major types of dosing, “Accumulation Factor”, and how to calculate the loading dose and the rate of infusion to achieve the desired Css.

He also demonstrates the applications of a loading dose with distinct diagrams.

What do you think of “Accumulation Factor”? Please leave your thoughts below.


Prof. Daniel L. Brown

This article is from the free online

Clinical Pharmacokinetics: Dosing and Monitoring

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