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How to predict changes in serum concentration?

How to predict changes in serum concentration before they occur?

We can learn the timing to measure serum levels in this part.

Besides, we need to know which factor(s) affects Cav,ss ? Which factor(s) affects Cmax,ss and Cmin,ss? The relationship between k, dosing interval (tau), and serum concentration (C) is the key in this section.

Does tau or volume affect the AUC? Does k or clearance affect C0? Please leave your answer below.


Prof. Daniel L. Brown

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Clinical Pharmacokinetics: Dosing and Monitoring

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