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Factor(s) affects Low E and High E drugs

Factor(s) affects Low E and High E drugs

Prof. Brown clarifies the clearance of high E drugs and low E drugs.

We can learn the factors affect low E drugs, such as fu and intrinsic clearance. On the contrary, the factor affects high E drugs will be the liver blood flow.

There are several examples of high E and low E drugs. However, we don’t need to memorize them now.

There is a brain exercise on this concept. Make sure you understand this part, then move on to the next part.


Prof. Daniel L. Brown

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Clinical Pharmacokinetics: Dosing and Monitoring

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