The ideas pharmacists need to know about dosing Aminoglycosides and Vancomycin
How can we optimize efficacy and minimize toxicity when dosing aminoglycosides and vancomycin?
Based on pharmacokinetic and pharmacodynamic considerations, we can understand the importance of the killing type of an antibiotic. For instance, Aminoglycosides is concentration-dependent. On the contrary, Penicillin and Cephalosporins are time-dependent.
We can also learn the effect of “peak/ MIC” for a concentration-dependent drug, and the effect of “time above MIC” for a time-dependent drug.
Have you faced any related problems in your job or your study? Please share your experience below.
Please check the related file for week 5 course slides for your reference.
Educator:
Prof. Daniel L. Brown
Clinical Pharmacokinetics: Dosing and Monitoring
Clinical Pharmacokinetics: Dosing and Monitoring
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