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The ideas pharmacists need to know about dosing Aminoglycosides and Vancomycin

The ideas pharmacists need to know about dosing Aminoglycosides and Vancomycin

How can we optimize efficacy and minimize toxicity when dosing aminoglycosides and vancomycin?

Based on pharmacokinetic and pharmacodynamic considerations, we can understand the importance of the killing type of an antibiotic. For instance, Aminoglycosides is concentration-dependent. On the contrary, Penicillin and Cephalosporins are time-dependent.

We can also learn the effect of “peak/ MIC” for a concentration-dependent drug, and the effect of “time above MIC” for a time-dependent drug.

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Educator:

Prof. Daniel L. Brown


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Clinical Pharmacokinetics: Dosing and Monitoring

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