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Intermittent infusion dosing & AMG serum level analysis

Intermittent infusion dosing & AMG serum level analysis

We can morph two dosing equations to calculate Cpeak,ss for an intermittent infusion dosing regimen.

Prof. Brown illustrates two steps on Aminoglycoside serum level analysis.

How long will it take for the last peak concentration to drop down to the new trough? When to start a new dosing regimen? He takes an example from his previous work experience. You must provide a specific time to start a new dosing regimen.

How do you analyze the serum concentration of Aminoglycoside? And do you have any question(s) on when to start a new dosing regimen? We are looking forward to your feedback. Please share your thoughts below.


Prof. Daniel L. Brown

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Clinical Pharmacokinetics: Dosing and Monitoring

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