Lower exercise capacity in type 2 diabetes
Exercise intolerance in T2D patientsPeople with T2D have impaired cardiorespiratory fitness and exercise tolerance compared with non-diabetic peers of similar age, weight and activity levels. This is manifested in:
- Reduced maximal aerobic capacity, expressed as maximum oxygen uptake (VO2 max)
- Slower overall rate of adjustment of pulmonary oxygen uptake (VO2 kinetics) and limb blood flow (blood flow kinetics) to submaximal constant-load exercise
- An important consequence of this exercise intolerance, observed in individuals with T2D, is that they perceive even light to moderate exercise, such as routine daily activities like climbing stairs, as more difficult than healthy peers. This often leads to a sedentary behavior or physical inactivity, and increased risk of cardiovascular outcomes and mortality (Wei et al, 2000).
Exercise Prescription for the Prevention and Treatment of Disease
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