Using HGVS nomenclature for DNA sequence changes
Just as alterations in chromosome structure and number are described using the International System for Human Cytogenetic Nomenclature (ISCN), changes to the DNA sequence are also described by an internationally agreed system, known as HGVS nomenclature.
If you visit the HGVS nomenclature website you will see that the system is very detailed and complex, but it is essential to have such a common language so that scientists across the world can each understand what the others have reported.
In other parts of this course you will see HGVS nomenclature used to describe variants in DNA sequences – when you see the nomenclature in a video or article you might want to pause and review the meaning to help familiarize yourself with the HGVS system.
Understanding Genetic Disorders: How DNA Influences Health
Understanding Genetic Disorders: How DNA Influences Health
Reach your personal and professional goals
Unlock access to hundreds of expert online courses and degrees from top universities and educators to gain accredited qualifications and professional CV-building certificates.
Join over 18 million learners to launch, switch or build upon your career, all at your own pace, across a wide range of topic areas.
