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Global Point Prevalence Survey (GPPS)

Read how the Global Point Prevalence Survey offers a tool to measure and monitor antimicrobial prescribing and resistance in hospitals worldwide.
World global with dots connected across continents
© London School of Hygiene & Tropical Medicine

The Global Point Prevalence Survey of Antimicrobial Consumption and Resistance (Global-PPS) offers a simple, freely available web-based tool to measure and monitor antimicrobial prescribing and resistance in hospitals worldwide. The Global-PPS has established a global network of hospitals conducting point prevalence surveys and provides quantifiable measures to assess and compare quantity and quality of antimicrobial prescribing and resistance in hospitalized adults, children, and neonates worldwide. The Global-PPS creates global awareness about antibiotic use and resistance and is instrumental in planning and supporting national and local stewardship interventions in a range of resource and geographical settings.

Purpose of the Global-PPS:

  • Monitor rates of antimicrobial prescribing and resistant bacteria in the hospital
  • Benchmark between hospitals, countries, regions
  • Identify targets to improve quality of antimicrobial prescribing
  • Identify healthcare associated infections (HAI)
  • Help designing hospital interventions to promote prudent antimicrobial use (Antibiotic Stewardship) and improve patient health
  • Assess effectiveness of interventions through repeated PPS
  • to prevent intervention-related HAIs

Note that this is a point prevalence survey. This means data on antibiotic use and the use diagnostics to commence treatment with antibiotics are collected in a hospital for a selected day. This gives the picture of antibiotic use in a day and can be repeated after interventions to measure the impact.

Different data collection forms are available for different hospital wards. The data collected can be keyed into a web-based system that permits analyses and comparison with other regions of the world.

In terms of diagnostics, the Global-PPS collects data on the use of biomarkers such as Procalcitonin (PCT), C-reactive protein (CRP) etc, the type of sample and the most relevant value. Data is also collected on culture sent to the lab before initiation of antibiotics. This provides data on whether patients were placed on antibiotherapy after diagnostic testing.

The data collection can be done at hospital, local, national, regional, and global levels. Data collection is on a weekday and not on weekends.

World map showing countries where databases include more than 300,000 patients allowing for the benchmarking of hospital from similar settings, same country, region and time periods (Click to expand)

Source: https://www.global-pps.com/wp-content/uploads/2021/03/3-VOLETS-GLOBAL-PPS.pdf

Map showing number of countries enrolled or participating in the Global-PPS (As of 2019)

Number of countries enrolled or participating in the Global-PPS (As of 2019)

How to enrol

To enrol your hospital, please visit the Global-PPS website and sign up to join the global effort: www.global-pps.com

© London School of Hygiene & Tropical Medicine
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