Alzheimer’s disease

Symptoms develop gradually over years. There is confusion, disorientation – people tend to get lost in places they know well, and there are difficulties in organising and making plans.

Memory is affected, particularly short term memories. It tends to be easier to recall episodes of life from years ago than what was for dinner today.

Some affected people become easily agitated, aggressive and demanding, and suspicious of what people around them are up to. These features are mild and occasional initially and steadily become more severe and all-consuming.

As degeneration extends to wider brain regions there is global physical deterioration. ‘Sulci’ are crevices that enlarge, giri are folds or ridges that deplete