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Renal Drug Recovery & Excretion Pathways : Mechanism

Renal Drug Recovery & Excretion Pathways : Mechanism

In this step, Prof. Lee clarifies Renal Drug Recovery and renal excretion pathways.

To begin with, high urinary recovery (>80%) indicates that the drug is primarily excreted by the kidneys, such as Aminoglycosides and Cephalosporin. Therefore, drugs with high urinary recovery require dosing adjustment in patients in renal failure.

Besides, we can review the three excretion ways again, including filtration, secretion, and reabsorption.

Finally, we can tell the mechanism of renal clearance based on the value of the creatinine clearance.

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Pharmacokinetics: Drug Dosing in Renal Disease

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