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Risk Factors for Cisplatin & Goal of therapy

Risk Factors for Cisplatin & Goal of therapy

In this step, Prof. Chen talks about Cisplatin, the goal, and benefits of therapies, and how to use diuretics.

First, Cisplatin is used in chemotherapy with high excellence for nephrotoxicity. Therefore, hydration is very important. After good hydration and the treatment, the patient will recover gradually.

Besides, the first goal of the therapy is to limit further nephrotoxic event and to allow the kidney to recover on its own. The second goal is to reduce further sequelae associated with ARF.

For diuretics, we should notice two things. If a patient develops resistance to diuretics, we need to see if there is any drug that reduces renal blood flow. Also, If a patient has volume depletion or has no adequate volume, we could not use diuretics.

Do you have any experience with patients who are resistant to diuretics?
How do you suggest the medication? Please share it below.

This article is from the free online

Pharmacokinetics: Drug Dosing in Renal Disease

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