The Fermentation Conditions
The rice bran fermentation requires enzymes from yeasts. In the previous video, we know that the fermentation process enriches nutrition and may benefit our health. The fermentation process is a …
Course: Agriculture and Nutrition
Intestinal Microflora, Involved in IgA Antibody Production
In this video, Professor Nochi demonstrated that the disturbance of gastric microflora caused by vancomycin, dramatically reduced the IgA producing plasma cells, and similar results were shown in the milk …
Used of Antibiotics Against Gastric Microflora
The intestinal colon consists of a variety of bacteria, some may beneficial/pathogenic to human health, and does the disturbance of gastric microflora, especially the use of antibiotics, will have any …
SCID Mice – Identifying the Main Source of Maternal IgA Production
SCID (Severe combined immunodeficiency) mice that lack T cells and B cells, which is commonly used to investigate the immune system network. And SCID transfer with inguinal lymph node or …
Ig Production with Experiment of LTβR Deficient Mice
LTβR is essential for the development of secondary lymphoid tissues except the spleen. By using LTβ knockout mice, Professor Nochi demonstrated that the spleen does not participate in the maternal …
Uniqueness of Mucosal Immunity System – M cells and Peyer’s Pathces
Professor Nochi demonstrated that the CCL28 was critical for maternal IgA production, but B-cells do not mature in the breast tissue but in the lymphoid tissue. And the very unique …
Concentration of IgA in Milk during Lactation
The concentration of IgA in milk increases gradually during lactation. Among them, there is one essential system to help maintain the mammary gland structure. Professor Nochi will explain further a …
Recruitment of IgA-producing Plasma Cells into the Mammary Gland
IgA producing cells accumulate after weeks of parturition. The research team used two markers: B220 and IgA to distinguish their changes during pregnancy, parturition, lactation and weaning.
Development Process of Mammary Gland
The mammary gland distinguishes mammals from all other animals with its unique anatomical structure that secretes milk for the nourishment of the newborn. This video gives us a brief rundown …
How are Antibodies Transferred to Neonates from the Mother?
In this video, professor Tomonori NOCHI explains how maternal antibodies are transferred to neonates. Basically, through breastfeeding, the mother can provide nutrition as well as immune bioactive factor to the …
IgA Production in the Mammary Gland
As mentioned in the previous video, the breast milk contains several antibodies. Among them, Immunoglobulin A (IgA) is considered the main and most important one. This video brings out that …
Milk Productions And Maternal Antibody Productions
This week, we turn our attention to husbandry. This video introduces the progress of the cattle lactation cycle and some of the topics we are going to explore, including the …
Possible Effects of FRB in AHR Ligand
Prof. Shirakawa suspected that the protective effects of FRB were via AhR(Aryl Hydrocarbon Receptor), so he further investigated the mechanism by using AhR deficient knock-out mice(KO). After DSS-administrated induced UC, …
FRB Effects in Tryptophan Levels, and SCFA
FRB has already shown protective effects in UC murine models. And the research team further found out that FRB could increase stool short-chain fatty acids (SCFA), which represents anti-inflammatory potential. …
FRB Against DSS Induced Colitis Model
DSS has demonstrated its function of inducing ulcerative colitis in murine models. Administrating FRB to the UC mice, the research team found that FRB could not only improve body weight …