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Course overview

Hello, Learners! Welcome to our pharmacokinetics series. I am Prof. Shawn Chen, the main educator of this course. The international group of instructors for this course are: Daniel Brown, Pharm …

Which factor(s) impacts the loading dose ?

Continuing from the previous video, Prof. Brown specifies how a loading dose relates to the volume of distribution (V). He shows the relationship between elimination and accumulation during a drug …

Overview of this week

This week, Professor Daniel Brown is going to explain the dosing basics, and how to determine the right amount of drug for a patient. Summary of Week 2: Compare and …

The factors affect Clearance : Summary

Prof. Brown explains the reason why protein binding (fu) changes only matters for highly protein bound drugs and how it influences clearance (CL). Another factor that affects clearance (CL) is …

What is the “Fish Tank Model” ?

In this video, Prof. Daniel Brown first introduces the assumptions and ground rules for this course. He illustrates the importance of focusing on practical patient care rather than a laboratory …

First week overview

What can you expect to learn from this week? Professor Daniel Brown will explain the topic: The Fish Tank – A Simplified Model of First-Order Elimination. Summary of Week 1: …

A Consensus Review of Vancomycin

Vancomycin is a glycopeptide antibiotic. It is one of the most widely used antibiotics in the United States for the treatment of serious gram-positive infections. Please read the article. The …

Summary : Case practice

How to calculate the Cmax and Cmin on Vancomycin IV bolus? How to monitor trough level of Vancomycin at steady state? How to revise Vancomycin dosing and when? (We are …