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The endogenous opioid system

In the last step, you touched upon endogenous opioid peptides. In this step, Dr Seung Cheol Kim, Pain Medicine Fellow at the Royal National Orthopaedic Hospital, and Dr Fausto Morell-Ducos, …

Pharmacokinetics

In this step, Dr Harriet Scott, Specialty Registrar in Anaesthesia and Pain Medicine at Barts Health, and Dr Lesley Bromley, retired Consultant and Senior Lecturer in Anaesthesia and Pain Medicine …

Pharmacodynamics

In this step, Dr Harriet Scott, Specialty Registrar in Anaesthesia and Pain Medicine at Barts Health, and Dr Lesley Bromley, retired Consultant and Senior Lecturer in Anaesthesia and Pain Medicine …

Case discussion

As you have seen over the last four steps, the perioperative pain management of patients with opioid tolerance and opioid use disorder (OUD) poses a number of challenges. In this …

Postoperative pain management

In this step, Dr Fausto Morell-Ducos, Consultant in Anaesthesia and Pain Medicine at UCLH, discusses current postoperative pain management recommendations which aim to reduce the incidence of opioid-related averse drug …

Modified-release opioids

In this step, Dr Jane Quinlan, Consultant in Anaesthesia and Pain Medicine at Oxford University Hospitals and Honorary Senior Lecturer at Oxford University, discusses why modified-release opioids are no longer …

Postoperative pain assessment

In this step, Dr Fausto Morell-Ducos, Consultant in Anaesthesia and Pain Management at UCLH, discusses the multidimensional assessment of pain following surgery. As you discovered in Week 1, the main …

Opioid-sparing anaesthesia and analgesia

Could reducing or even avoiding the use of opioids during general anaesthesia and in the early postoperative period have a role to play in promoting opioid stewardship? In this step, …

Opioid-free anaesthesia

In this step, Dr John Whittle, Consultant in Anaesthesia, Perioperative and Critical Care at UCLH and Associate Professor of Perioperative Medicine at UCL, discusses the evidence base behind opioid-free and …

Psychological risk factors

In this step, Dr Kelley Corcoran, Consultant Clinical Psychologist and Clinical Lead for the UCLH Complex Pain Team, discusses the psychological risk factors associated with the development of chronic post-surgical …

What can we do to prevent PPOU?

In this step, Dr Jane Quinlan, Consultant in Anaesthesia and Pain Medicine at Oxford University Hospitals Trust and Honorary Senior Clinical Lecturer at the University of Oxford, outlines what practical …

Low- and middle-income countries

In this step, Dr Fausto Morell-Ducos, Consultant in Anaesthesia and Pain Medicine at University College London Hospitals, discusses opioid prescription patterns in low- and middle-income countries (LMICs). The WHO estimates …

Perioperative opioids and the opioid epidemic

In this step, Dr Jamie Smart, Consultant in Anaesthesia and Pain Medicine and Chair of the Opioid Stewardship Committee at University College London Hospitals, discusses how perioperative opioid use has …

Introduction to opioid pharmacology

In this step, Dr Lesley Bromley, retired Consultant and Senior Lecturer in Anaesthesia and Pain Medicine at University College London, introduces some of the pharmacological concepts you will need to …

Setting up a transitional pain service

In this step, we hear from Dr Hance Clarke, Director of Pain Services at the Toronto General Hospital and President-Elect of the Canadian Pain Society, Dr Praveen Ganty, Staff Anaesthesiologist …