Mark Hoppé

Mark Hoppé

I am a Public Health entomologist with a particular interest in integrated mosquito vector control and insecticide resistance management. When I'm not working with mosquitoes I enjoy cycling.

Location Basel, Switzerland


  • Greetings Issack, I hope the course meets your expectations.

  • I'm glad you found the article useful. The article can be used in your teaching, but please acknowledge the author and the copyright of the University of Basel.

  • That is a really good question. There are 'gene drive' approaches, where a genetically modified mosquitoes could be used to spread specific genes within the mosquito population. These genes could potentially prevent future generations of the mosquitoes developing, reducing, or even eliminating, the population. Genes that prevented the Anopheles mosquitoes...

  • Good point. The principles of integrated vector management, IVM, and insecticide resistance management, IRM, are broadly the same for Anopheline malaria vectors and the Aedes spp. vectors of viral diseases. However, the actual control measures may be different due to their different habitats, feeding behaviours, and the local context.

  • A good summary

  • Greetings Filémon, I hope you find the course useful

  • Welcome John, I hope you find the course useful.

  • The unchecked use of pesticides doesn't make the mosquitoes more 'deadly', but it can make them much harder to control, reducing our ability to prevent the diseases they can vector. So it can make the situation, or environment, more deadly, as we are less able to protect people from mosquito borne diseases.

  • Well said, community engagement is the foundation to build on.

  • Good points, too often we think only on the global scale, but in the end, malaria vector control is undertaken at the local level. Without engaging with all stakeholders, it will be a much harder task to eliminate malaria.

  • Welcome to the MOOC Huicong

  • Welcome Alemayehu, I hope you find some useful information in the course.

  • I like that analogy.

  • Some good points, this will be a challenge for many locations as they start to approach malaria elimination.

  • Some good points, an 'integrated' approach will always be the best way. Reducing mosquito numbers by making the environment less favorable to them is an important step, especially when it is human activities that make the favorable environment in the first place. This is addressed in several steps of the MOOC.

  • Hello Flavia, welcome to the course, I hope you do find useful information here.

  • Some good thoughts Daniel

  • Hi Ruth, I hope the course meets your expectations.

  • Hello James, I hope you find this course useful.

  • Greetings, I hope you find the course interesting and informative.

  • Welcome to the course, I hope you find it useful.

  • I hope you find the course useful.

  • Hello Ahmed, I hope you find the course useful.

  • Greetings Jeremiah, welcome to the MOOC.

  • Welcome Candice, I hope the course lives up to expectation.

  • Some very good points, especially about town planning and improved drainage. Thanks for sharing your thoughts.

  • Welcome! I hope you find the course useful and informative.

  • Welcome, I hope you find the course useful.

  • Some very good points.

  • Welcome Mohammed, you make some good points, I look forward to hearing your contributions in later steps of the course.

  • That is correct, but within the 'adulticides', that kill the adults, and the 'larvicides', that kill or prevent the larvae from developing, there are a number of different classes of insecticide. This is important to know for effective resistance management.

  • Welcome to the MOOC Stephen!

  • Welcome Isaac, I hope this course will help you to gain more knowledge about malaria control and insecticide resistance management

  • Thanks Anna, a good summary. I think the key is to have integrated approaches in the wider context of 'One Health'.

  • Good points

  • Hello Monica, I hope you find the course interesting and useful

  • Hi, welcome to the course. I hope you find the course useful.

  • Non-vector control exposure, is referring to the mosquitoes coming into contact with the insecticides used for vector control in other situations where they weren't used specifically for mosquito control. e.g. if insecticides from the same mode of action groups are used in agriculture. In this situation the mosquitoes may rest on treated crops, or the larvae...

  • Good point that a rotational approach to the use of insecticides from different MoA classes will help delay resistance development. But, the scientists and chemists can only try to design novel and improved insecticides, it is those who design and fund the control programmes that decide which interventions to use, and should be encouraged to implement IRM in...

  • Hi Julia, This MOOC doesn't look in any further detail at the parasites that cause malaria. There are a number of excellent online courses that do, so look them up if would like to know more about the Plasmodium. Good question about whether the parasite is also changing. Yes, is the answer, and there is a lot of concern about drug resistance in the Plasmodium....

  • It has been estimated that between 2000 and 2015 663 million cases of malaria were averted through the use of insecticidal vector control interventions. That's a lot of people who think the use of LLINs and IRS was a clever idea. See

  • Hi, the subject of this course is insecticide resistance management. This has to be set in the context of wider vector control, but that isn't the main topic. The course aims to set IRM firmly in the context of Integrated Vector Management (IVM). In IVM (also called IV Control) the aim is to minimise the interaction of vector mosquitoes and humans. IVM covers...

  • The WHO study did not include untreated mosquito nets, but compared insecticide treated nets in areas where there were pyrethroid resistant or susceptible mosquito populations. The conclusion is that even if there are pyrethroid resistant mosquitoes present, a pyrethroid treated bed net still provides some protection against malaria. The comparison with an...