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Certificate of Achievement
has completed the following course:
Pharmacokinetics: Drug Dosing in Renal Disease
This online course explored the principles of pharmacokinetics and drug dose adjustment. The course covered topics including Pharmacokinetics and dosing regimen in renal failure, dosing regimen and therapeutic drug monitoring in renal failure.
6 weeks, 2 hours per week
Shawn Chen
Professor, School of Pharmacy
Taipei Medical University
Transcript
Learning outcomes
- Explain basic physiology of the kidneys
- Calculate renal clearance by excretion rate method / renal clearance by urinary recovery method
- Describe pharmacokinetic factors that affect dialysability of drugs
- Describe the most common causes of chronic renal failure
- Assess an appropriate therapy for chronic renal failure and secondary complications
Syllabus
In this course, you will learn the principles of pharmacokinetics and drug dose adjustment in renal disease.
Week 1 - Renal Physiology and Function
Learn the basic physiology of the kidneys and describe filtration, secretion and reabsorption of water, electrolytes and small molecular weight non-electrolytes
Week 2 - Pharmacokinetics and Dosing Regimen in Renal Failure
Understand the mechanisms of renal drug excretion
Week 3 - Dosing Regimen And Therapeutic Drug Monitoring in Renal Failure
Become proficient at interpolating or extrapolating concentration based on first order kinetics
Week 4 - Dosing Regimen in Renal Dialysis
Learn to calculate dialysis clearance using the A-V difference method/ using dialysate concentration
Week 5 - Acute Renal Failure
Explore pathophysiology and the most common causes of prerenal, intrinsic, and postrenal
Week 6 - Chronic Renal Failure
Learn to describe the typical clinical presentation of chronic renal failure
Issued on 17th May 2020
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