Certificate of Achievement
has completed the following course:
Bacterial Genomes II: Accessing and Analysing Microbial Genome Data with Artemis
This course covered the principles of microbial bioinformatics analysis and comparative genomics. Using Artemis, an open source genome browser, whole bacterial genomes were investigated: comparisons of reference and draft genomes were made; genome annotation and file formats were shown and together explored, GC (guanine-cytosine) content and the use of this metric to analyse functional blocks in the genome was covered; and Artemis was used to compare two bacterial genomes and their gene content.
The Royal College of Pathologists (RCPath) has accredited this course for 15 Continuing Professional Development (CPD) credits. This applies to medical staff and clinical scientists in career grade posts who are enrolled with one of the Royal Colleges for CPD purposes.
3 weeks, 5 hours per week
Dr Rebecca Twells
Head of
Wellcome Connecting Science
Professor Nicholas Thomson
Group Leader, Bacterial Genomics and Evolution
Wellcome Sanger Institute, Wellcome Genome Campus
Transcript
Learning outcomes
- Collect, access, and download whole bacterial genomes from public repositories
- Investigate and navigate bacterial genomes and their annotation using Artemis
- Identify genomic regions with low/high GC (guanine-cytosine) content, often associated with virulence
- Perform simple comparative analyses between bacterial genomes
Syllabus
Week 1
- Multi-FASTA files
- Reference and draft bacterial genomes
- Introduction to Artemis, an open source genome browser
Week 2
- Genome annotation
- Genomic regions defined by GC (guanine-cytosine) content
- Accessing and downloading whole genome sequences
- Pathogenicity islands
Week 3
- Peer-reviewed project: Ecological niche adaptation between two Mycobacterium species
- Pseudogenes in Mycobacterium species
Accreditation
The Royal College of Pathologists (RCPath) has accredited this course for 15 Continuing Professional Development (CPD) credits. This applies to medical staff and clinical scientists in career grade posts who are enrolled with one of the Royal Colleges for CPD purposes.
Accredited by
Issued on 8th July 2020
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