Welcome to Week 3

In this penultimate week of the course we will introduce you to the analytical techniques that are applied to study the metabolome.

In the first few activities we will look at the design of experiments to analyse the metabolome and the preparation of samples.

The design of experiments is important in any scientific experiment. In metabolomics it is very important to ensure confounding factors are not introduced into the studying and that all sources of variance are controlled with the exception of the one under investigation.

A vast range of samples may be used in metabolomics studies, we will look at the different sample types that are commonly analysed and discuss the preparation methods that may be applied to extract the different classes of chemicals.

A number of analytical approaches may be applied to measure the metabolome. In this course we will focus on the application of mass spectrometry and liquid chromatography coupled to mass spectrometry to analyse the metabolome. We will look at both the advantages and applications of the approaches and illustrate how we are developing these approaches at the University of Birmingham.

Mark as complete

Remember to click the Mark as complete button when you have reached the end of a step and have understood everything. This will update your progress page and will help you to keep track of the steps that you have done. Any steps that you have completed will turn blue on your To do list.

Prove what you’ve learned with a certificate

If you want a record of your course, you can buy a Certificate of Achievement from FutureLearn.

The Certificate of Achievement is a great way to prove what you have learned on the course and as evidence of your Continuing Professional Development. This is a personalised certificate and transcript, detailing the syllabus and learning outcomes from the course. It comes as a printed certificate as well as a digital version which you can add to your LinkedIn profile. To qualify, you must have marked at least 90% of the steps in the course complete.

There is also the option to purchase a personalised Statement of Participation, to celebrate taking part. To be eligible for the Statement of Participation, you must mark at least 50% of the steps on the course as complete. This also comes in a printed and digital format and you can add it to your LinkedIn profile.

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This article is from the free online course:

Metabolomics: Understanding Metabolism in the 21st Century

University of Birmingham