Please take some time to read this paper published on Briefings in Bioinformatics. You can download PDF at the link below.
This article is a review article that showed some machine learning methods in bioinformatics. Different machine learning models have been shown such as supervised learning classification, regression, or clustering. Moreover, this article also shows the applications of them in different aspects of bioinformatics i.e., genomics, proteomics, systems biology, evolution and text mining.