Famous scientists who leveraged technology
As important as it is to take steps forward, it’s also necessary to look back and see those who helped clear the path for us.
Who are the famous scientists whose discoveries changed the world of biopharmaceutical technology?
It’s hard to tell, because so many scientists contributed to biotechnologies. With the help of my students of the Master Degree in Pharmaceutical Biotechnologies I will highlight some of the many contributions by famous and less famous scientists, whose enabling discoveries shaped up the knowledge and technologies behind the success of biological drugs and modern pharmaceutical research and applications.
Bibliography:
- A. Fleming Nobel Lecture 1945: Penicillin, December 11, 1945. https://www.nobelprize.org/uploads/2018/06/fleming-lecture.pdf
- F. Sanger Nobel Lecture 1958: The Chemistry of Insulin, December 11, 1958. https://www.nobelprize.org/uploads/2018/06/sanger-lecture.pdf
- F. Sanger Nobel Lecture 1980: Determination of Nucleotide Sequences in DNA, December 8, 1980. https://www.nobelprize.org/uploads/2018/06/sanger-lecture-1.pdf
- P. Berg Nobel Lecture 1980: Dissections and Reconstructions of Genes And Chromosomes, December 8, 1980. https://www.nobelprize.org/uploads/2018/06/berg-lecture.pdf
- G.J.F. Köhler Nobel Lecture 1984: Derivation and Diversification of Monoclonal Antibodies, December 8, 1984. https://www.nobelprize.org/uploads/2018/06/kohler-lecture.pdf
- C. Milstein Nobel Lecture 1984: From the Structure of Antibodies to the Diversification of the Immune Response, December 8, 1984. https://www.nobelprize.org/uploads/2018/06/milstein-lecture.pdf
Additional readings
- Reichert, J. Monoclonal antibodies in the clinic. Nat Biotechnol 19, 819–822 (2001). https://doi.org/10.1038/nbt0901-819
- Brekke, O., Sandlie, I. Correction: Therapeutic antibodies for human disease at the dawn of the twenty-first century. Nat Rev Drug Discov 2, 240 (2003). https://doi.org/10.1038/nrd1060
- Revers L, Furczon E. An Introduction to Biologics and Biosimilars. Part I: Biologics: What are They and Where Do They Come from? Canadian Pharmacists Journal / Revue des Pharmaciens du Canada. 2010;143(3):134-139. https://doi.org/10.3821/1913-701X-143.3.134
- Senior, M. Fresh from the biotech pipeline: fewer approvals, but biologics gain share. Nat Biotechnol 41, 174–182 (2023). https://doi.org/10.1038/s41587-022-01630-6
Getting to Know Pharmaceutical Biotechnologies: More than Science in a Lab
Getting to Know Pharmaceutical Biotechnologies: More than Science in a Lab
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