Skip main navigation

Advantages of oral versus IV antibiotic therapy

Advantages of oral versus IV antibiotic therapy
Intravenous drip in patients hand
© BSAC

The potential advantages and disadvantages of using oral and IV antibiotics for serious infections such as endocarditis, bone and joint infections and neurosurgical infections in the outpatient environment are outlined in the table below:

Table describing pros and cons of oral vs IV antibiotics in outpatients. For example - oral has higher convenience than IV, IV requires more contact with health services, and oral antibiotics have higher cost effectiveness if the efficacy is similar, and IV has lower cost effectiveness if the efficacy is similar.

(Click to expand)

Now read the papers below and consider the results of the OVIVA and POET trials.

Discuss with your fellow learners your thoughts on switching early from IV to oral therapy in serious infections given the emerging evidence from these trials.

Is this something you are, or would be, comfortable doing in your clinical practice?

Share your thoughts and experiences, and interpretations of the trials, with your fellow learners.

© BSAC
This article is from the free online

Intravenous to Oral Switch: Within Outpatient Parenteral Antibiotic Therapy (IVOST)

Created by
FutureLearn - Learning For Life

Our purpose is to transform access to education.

We offer a diverse selection of courses from leading universities and cultural institutions from around the world. These are delivered one step at a time, and are accessible on mobile, tablet and desktop, so you can fit learning around your life.

We believe learning should be an enjoyable, social experience, so our courses offer the opportunity to discuss what you’re learning with others as you go, helping you make fresh discoveries and form new ideas.
You can unlock new opportunities with unlimited access to hundreds of online short courses for a year by subscribing to our Unlimited package. Build your knowledge with top universities and organisations.

Learn more about how FutureLearn is transforming access to education