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PGD for risk genes?

This video features Caroline Presho, a BRCA mutation carrier, who has not used PGD for her children.

Caroline carries the BRCA mutation, an unexpected inheritance from her father.

Here she provides an insightful view on the implications of carrier knowledge in terms of personal health and family impact.

In Caroline’s case, she had to make a decision based on probabilities. The BRCA mutation increases a Xperson’s risk for breast and ovarian cancer. In fact, the BRCA mutation often predisposes to early, aggressive cancers.

The average age of onset of BRCA-associated cancers is only 51 years of age.

Points to consider: Imagine you were in Caroline’s shoes, having to make decisions about your future offspring based on probabilities and risks. What kind of information would you need to make your decision? Who would you go to for advice? What would you do?

This article is from the free online

Making Babies in the 21st Century

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