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Looking at chromosomes

In this step, we will learn about the different techniques which can be used to study the structure of chromosomes

Karen Marks, senior clinical scientist in cytogenetics, discusses the impact that array CGH (Array Comparative Genomic Hybridization) has had on clinical practice.

Karen describes the process of array CGH, where a patient’s DNA sample is compared against the reference DNA, that is considered to have no abnormalities. She also explains how to spot the imbalances in patients’ DNA.

Do you want to know more?

If you would like to know more about the development of array CGH, check out ‘Development and validation of a CGH microarray for clinical cytogenetic diagnosis’ from Genetics in Medicine.

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The Genomics Era: the Future of Genetics in Medicine

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