Certificate of Achievement
Mary Templeman Hogg - O'Rourke
has completed the following course:
Genomic Technologies in Clinical Diagnostics: Next Generation Sequencing
St George's, University of London
This online postgraduate level course explored how next generation sequencing (NGS) technologies are used in healthcare to investigate genetic disorders. The course described and contrasted a range of NGS platforms and their application to both clinical and research practice.
2 weeks, 5 hours per week
Katie Snape
Consultant and Senior Lecturer in Clinical Genetics
St George's, University of London
Kate Tatton-Brown
Consultant and Reader in Clinical Genetics
St George's, University of London
Transcript
Learning outcomes
- Demonstrate an understanding of the molecular principles underlying Next Generation Sequencing (NGS) technologies
- Identify appropriate applications of these technologies to clinical scenarios within both the diagnostic and research settings
- Design a panel of genes for analysis using Next Generation Sequencing technologies applicable to a specific clinical phenotype
Syllabus
- The changing landscape of genomics: From Sanger sequencing to Next Generation Sequencing
- Overview of Next Generation Sequencing platforms and their methodology
- Targeted resequencing
- Alignment, variant calling and annotation
- Other applications of Next Generation Sequencing beyond DNA sequencing
- Next Generation Sequencing in gene discovery
- Gene discovery in the research and diagnostics
- Next Generation Sequencing in clinical diagnostics: Single gene, gene panel sequencing, exome and genome sequencing
- How to design a gene panel
- The 100 000 Genomes project
- The transforming NHS: Genomics in mainstream practice
Accreditation
The course has been approved for distance-learning continuing professional development (CPD) by the Royal College of Pathologists (RCPath): for 10 CPD credits.
Accredited by
Issued on 22nd October 2019
The person named on this certificate has completed the activities in the transcript above. For more information about Certificates of Achievement and the effort required to become eligible, visit futurelearn.com/proof-of-learning/certificate-of-achievement.
This certificate represents proof of learning. It is not a formal qualification, degree, or part of a degree.
Free online course: