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The scope of cancer genomics

In this step, Professor Serena Nik-Zainal explains the landscape and scope of genomic testing in cancer.

In this step, we give the floor to Professor Serena Nik-Zainal, research professor at the National Institute for Health and Care Research and an honorary consultant in clinical genetics.

During this interview, Professor Nik-Zainal talks about:

  • her role in somatic cancer research;
  • how samples are taken for paired whole genome sequencing (WGS), and the benefits of this technology;
  • the shrinking distance between academic research and clinical practice;
  • what driver and passenger mutations are, and their roles in current and future research and treatment; and
  • what mainstreaming means in routine cancer care.

Although WGS is not yet a standard-of-care test for cancer in the NHS, the power and potential of this technology has huge implications for the future. Researchers like Professor Nik-Zainal are on the cutting edge, making discoveries that will truly change the way cancer treatment evolves in the coming years.

We will hear more from Professor Nik-Zainal later on in the course. For now, let’s get practical and explore the types of somatic cancer tests you should be familiar with.

This article is from the free online

Genomics in the NHS: A Clinician's Guide to Genomic Testing for Cancer (Solid Tumours)

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