Viewing a bacterial genome: How Chlamydia escaped detection

In this video, we show you how genome sequences are visualised using the Artemis software. We give an overview of what a bacterial genome sequences looks like and how resequencing is used to determine differences between similar bacteria. We show how this approach was used to identify how a strain of Chlamydia escaped detection, causing a disease outbreak.

In this video we mention a PCR-based diagnostic test. When used in diagnostic tests the Polymerase Chain Reaction (PCR) allows a small sequence of a genome, for which the sequence is known, to be detected.

OPTIONAL: If you wish to know more about this tool, you can download the Artemis software yourself and try loading the data from this FTP site: ftp://ftp.sanger.ac.uk/pub/pathogens/ar11/FutureLearn/.

For more on analysing bacterial genomes and on the use of Artemis tool, you can follow one of our WGC ACSC courses here: Bacterial Genomes: Accessing and Analysing Microbial Genome Data