Course: Bacterial Genomes: Disease Outbreaks and Antimicrobial Resistance

Bacteria can be transmitted to and from humans via direct or indirect mechanisms. Direct transmission can occur through person-to-person contact, when an infected person touches or exchanges bodily fluids with …

Epidemiology is the study of patterns and trends in disease to understand their causes. In the context of pathogen transmission, epidemiology is often used to analyse the pattern of disease …

Adam and Josie introduce Week 2 of the course, where we explore the transmission of disease and how genomics can help us understand this process.

The emergence of a killer outbreak In mid-May 2011, German health authorities reported an outbreak of a rare type of Escherichia coli amongst three patients with haemolytic uremic syndrome (HUS) …

Congratulations on completing week 1 of the course. We hope you enjoyed it. This week you have learnt what bacteria are, how they are classified and that some types of …

In this video, we show you how genome sequences are visualised using the Artemis software. We give an overview of what a bacterial genome sequences looks like and how resequencing …

In this article, we describe how the Artemis genome browser displays genome sequences. A genome browser is a piece of software that allows us to visualise a genome sequence and …

We have learned a lot from sequencing and examining small numbers of reference genomes. So we have summarised some of the lessons learned for you below with links to research …

In the early days of genome sequencing, little was understood about the structure of genomes and it was a very expensive exercise. The first human genome sequence, finished around the …

The genome of an organism consists of one or more stretches of DNA, which can be thought of as strings of the letters A, T, G and C. A particular …

In this video interview, Professor Julian Parkhill explains what bacterial genomes can tell us about how certain bacteria cause disease. After viewing the video, in the Comments area, share one …

There are several different ways in which bacterial genomes can change. Most of the time, these changes will not be important for disease. However, some changes can cause a disease …

DeoxyriboNucleic Acid (DNA) is a long molecule made up of a repeating string of just four different chemicals (nucleotides or bases). These are adenine (A), thymine (T), guanine (G) and …

Learn more from six researchers who work here at the Wellcome Sanger Institute. Susannah Salter is using genome sequencing to learn how a new species of bacteria could be grown …

In the media, we often hear about good and bad bacteria. What do we mean by this? We cannot escape bacteria, they are everywhere. While a few species cause disease …