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Vaccines and AMR Case Study: Multi-Drug Resistant Tuberculosis

This video discusses a case study focused on Multi-Drug Resistant Tuberculosis.

The interview above, with Professor Helen McShane from the Jenner Institute at the University of Oxford, discusses the need for a new TB vaccine, its importance in preventing the spread of MDR TB and the difficulties of developing a new vaccine against TB.

Tuberculosis (TB), a disease caused by the bacteria Mycobacterium tuberculosis, is one of the top 10 causes of death worldwide and a leading killer for HIV positive patients.

Anti-TB medicines have been used for decades and strains that are resistant to one or more of the medicines have been documented in every country surveyed. Drug resistance emerges when anti-TB medicines are used inappropriately, through incorrect prescription by health care providers, poor quality drugs, and patients stopping treatment prematurely.

Increasing numbers of infections due to multi-drug resistant (MDR) and extensively drug resistant (XDR) TB is a current international public health crisis and poses a health security risk.

Watch this video made by Aeras to understand the problem of antimicrobial resistance in TB and the potential impact of a vaccine.

This is an additional video, hosted on YouTube.

In the resources section below you will find a publication detailing the effects of drug resistant TB and what is currently being done to develop new vaccines to fight the disease.

This article is from the free online

The Role of Vaccines in Preventing Infectious Diseases and Antimicrobial Resistance

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