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Acknowledgements

Many thanks to all those who are and were involved in the ‘Bacterial Genomes: Accessing and Analysing Microbial Genome Data’ course’s development, refinements, and presentations. Course Lead Educators and Lead …

What you have learnt in this course

We hope you have enjoyed your time with us. During the length of this three-week course you have become familiar with whole genome sequences, and the tools we can use …

Concluding discussion, reflection and planning

You have reached the end of the course. Congratulations! Completing the course has helped you to: discover the basic principles of microbial bioinformatics analysis, and comparative genomics acquire skills in …

Exploring pseudogenes in Mycobacterium leprae

In this Step you will explore 5 different pseudogenes across the Mycobacterium leprae genome, you will investigate their annotation and make comments on their GC content. Previously we described just …

Calculating GC for regions of the genome

In this Step, we will learn that GC content changes along a genome. We will also learn to display GC content in Artemis and what genome features can be associated …

Annotation files

In this article we learn how information about genes and proteins found in genomes can be stored in files. Genomic features that are found in the genome can be stored …

Finding protein function: Functional annotation

In addition to finding where genes are in the genome, it is possible to find more information about the function of the proteins they encode. Almost universally, sequence similarity tools …

Finding and annotating genes in a genome

In this course we will focus on the annotation of coding sequence, that is to say, those regions of the genome that form the template for making proteins. From now …