Finding protein function: Functional annotation
In addition to finding where genes are in the genome, it is possible to find more information about the function of the proteins they encode. Almost universally, sequence similarity tools …
Course: Bacterial Genomes II: Accessing and Analysing Microbial Genome Data Using Artemis
Finding and Annotating Genes in a Genome
In this course we will focus on the annotation of coding sequence, that is to say, those regions of the genome that form the template for making proteins. From now …
Introduction to annotation
In this article we set the scenario for the exploration of genome annotation. DNA contains the code or instructions to make proteins and other components of cells. These instructions are …
Viewing your first DNA sequence in Artemis
In this video we will demonstrate how to open a sequence FASTA file in Artemis. We will explore the look of Artemis and some basic tools for navigation. Before you …
The Genesis of Artemis: Professor Julian Parkhill and Dr. Anna Protasio
In this video interview, Professor Julian Parkhill from the Wellcome Sanger Institute shares his experience of the creation of Artemis with Dr. Anna Protasio. Julian talks about the advances in …
What is a genome browser and why do we need one?
In this article, we introduce genome browsers, which are revolutionary tools that help us to understand genes in the context of whole genomes. What is a genome browser? A genome …
What’s the difference between a draft and finished genome?
Many bacterial genomes are nowadays presented as finished genomes rather than draft genomes. This is because third generation sequencing technologies provide such long sequences that whole bacterial chromosomes can be …
Genomes in chunks
In this Step we will learn how to represent large multi-piece genomes in one file. As it is the case for genes and proteins, whole genome sequences can also be …
How much DNA is too much DNA?
In this Step we will cover some of the common terminology used to describe large genomes. DNA content varies dramatically from one organism to the next. For example, although viruses …
Getting you started and the glossary
In this Step we go through some housekeeping so you can get ready to achieve your very best during this course. Resources you will need Although a lot of the …
Meet our Course Team: Leads, Educators and Developers
Dr. Anna V. Protasio Lead Educator and Developer I am a researcher in molecular biology of infectious diseases and an instructor for the Working with Pathogen Genomes course organised by …
Wrapping Up Artemis Practice
In this screencast we demonstrate the previous exercise step by step. You will review how to open a DNA file and load its annotation. You will also learn how to …
Whole-genome view of GC content
In addition to looking at the fine detail of the annotated features it is also possible to look at the characteristics of the DNA covering the region displayed. This can …
How can Artemis provide structural data of a gene?
It is possible to use Artemis to display certain characteristics of a gene that is of interest. In the ‘View’ menu, select the ‘Feature Plots’ option. This selection will open …
Getting the nucleotide and amino acid sequences
Sometimes it is useful to extract the sequence of our gene or protein of interest from Artemis. Here you will learn how to do just that! In order to extract …
These articles are from the online course:
Bacterial Genomes II: Accessing and Analysing Microbial Genome Data Using Artemis