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An article explaining what can be done to combat antimicrobial resistance.
What's next? by Crystal
© UoD 和 BSAC

美国感染病学会将抗菌药管理描述为:

“通过促使选择最佳的抗菌药物给药方案、剂量、治疗持续时间和给药途径,设计整合的措施用于改>善和测量抗菌药的适当使用。抗菌药管理寻求达到与抗菌药使用有关的最佳临床疗效,最大限度地>减少毒性和其他不良事件,降低治疗感染的医疗成本,并减少耐药菌的选择压力。”

开具抗生素处方者有责任按照管理原则开具处方,而医疗组织中的抗菌药管理项目通常由多学科管理团队指导。此团队的组成取决于本地资源。推荐的成员包括医学微生物专家和/或感染病医生、抗菌药师、感染控制护士、流行病医生和信息系统专家。管理团队的工作分成两个主要领域:处方规范和临床疗效的监管,以及旨在获得最佳抗生素处方的干预措施设计和实施。

监管包括测量流程,例如抗菌药使用(各种数量统计以及对是否遵守抗生素处方原则的衡量)、生态学影响(抗生素耐药性检测和艰难梭菌感染人数)以及临床疗效(发病率和死亡率)。干预措施分为三个主要类别:结构型、劝导型和限制型(Davey P 等人:Cochrane database of systematic reviews 2013)。

© UoD 和 BSAC
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抗菌素管理: 管理抗生素耐药性

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