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Discussing the paper, "Randomised Trial of Rapid Multiplex Polymerase Chain Reaction-Based Blood Culture Identification and Susceptibility Testing"
Staphylococcus aureus Bacteria
© UoD 和 BSAC

在 2015 年发表的一篇由 Banerjee 所著的论文 对快速多重基于聚合酶链反应的血液培养鉴定和敏感性测试的随机试验 中,详细地介绍了一 项临床试验,评估对阳性血液培养瓶应用的快速诊断方法多重实时 PCR)所产生的影响的临床试验。该试验包括:

  • 传统血液培养处理组
  • 新快速方法组以及
  • 新快速方法和与抗菌药物管理团队直接交流的组合。




“ 在此随机试验中,BCID 方法可缩短病原体鉴定所需的时间,但是只有当 BCID 测试与抗菌药物管理结合时,才会缩短适当抗菌药物降级和升级所需的时间。采用快速血液培养诊断时应结合抗菌药物管理”。

准确的抗菌药物 诊断并非总是能产生适当的抗菌药物处方。知识(认知)和行动(行为)属于不同的维度;这可以解释在本临床试验中观察到的认知-行为差异。



这些是处方人员在考虑降级时最常提出的问题。必须激励处方人员完成降级。激励处方人员简化抗菌药物 疗法的最佳途径是告诉他们,病原治疗在确保临床疗效的同时还具有生态学效益。

在第 5 周中您将会学习到,除了缺乏知识,处方变更(行为变化)还面临着一些障碍。


© UoD 和 BSAC
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抗菌素管理: 管理抗生素耐药性

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