History of disease outbreaks and their impact 

In this step, Jimmy Whitworth (LSHTM) explains the history of outbreaks, which has been traced back to Ancient Rome and Greece. This step covers the diseases that caused outbreaks historically and the progress that was made to control them, including the critical development of vaccines. This step also explains the development of the International Health Regulations and its role as a framework for helping countries prepare and respond to outbreaks.